Synthesis of polysubstituted pyrroles via [3 + 2]-annulation of aziridines and β-nitroalkenes under aerobic conditions.
نویسندگان
چکیده
Polysubstituted pyrroles were regioselectively synthesized in moderate to good yields via the copper acetate-catalyzed [3 + 2] annulation reaction of readily accessible aziridines and nitroalkenes. This reaction was proposed to proceed through a key azomethine ylide intermediate generated by selective C-C bond cleavage of the aziridine followed by annulation with nitroalkenes under aerobic conditions.
منابع مشابه
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 8 شماره
صفحات -
تاریخ انتشار 2014